Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis

Chest pain in kidney transplant patients is usually caused by cardiac or pulmonary problems. However, it may be rarely caused by opportunistic esophageal infections. A 66-year-old female kidney transplant recipient was admitted because of chest pain. She had been treated with high-dose steroid and i...

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Main Authors: Seok Hyung Kang, Myong Ki Baeg, Sun-Hye Ko, Hyunjung Hwang, Sang Yeop Yi, Sung Jin Moon, Jeongkeun Park
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2019-03-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
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Online Access:http://helicojournal.org/upload/pdf/kjhugr-2019-19-1-61.pdf
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author Seok Hyung Kang
Myong Ki Baeg
Sun-Hye Ko
Hyunjung Hwang
Sang Yeop Yi
Sung Jin Moon
Jeongkeun Park
author_facet Seok Hyung Kang
Myong Ki Baeg
Sun-Hye Ko
Hyunjung Hwang
Sang Yeop Yi
Sung Jin Moon
Jeongkeun Park
author_sort Seok Hyung Kang
collection DOAJ
description Chest pain in kidney transplant patients is usually caused by cardiac or pulmonary problems. However, it may be rarely caused by opportunistic esophageal infections. A 66-year-old female kidney transplant recipient was admitted because of chest pain. She had been treated with high-dose steroid and immunosuppressants for acute T-cell-mediated rejection. Cardiologic and pulmonary evaluations had normal results. Endoscopic examination revealed three clear ulcerative lesions in the esophagus. Histological and immunohistochemical staining of the endoscopic biopsy specimens revealed coinfection of herpes simplex virus and cytomegalovirus. The patient was treated with intravenous ganciclovir for 2 weeks. Her symptoms completely resolved, and follow-up endoscopy revealed complete healing of the previous ulcers. Viral esophagitis should be considered in the differential diagnosis in kidney transplant recipients presenting with chest pain.
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institution Kabale University
issn 1738-3331
language English
publishDate 2019-03-01
publisher Korean College of Helicobacter and Upper Gastrointestinal Research
record_format Article
series The Korean Journal of Helicobacter and Upper Gastrointestinal Research
spelling doaj-art-7046ffb3e9a5476fadbb08d23f7e9ff92025-08-20T03:56:13ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312019-03-01191616410.7704/kjhugr.2019.19.1.61547Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus EsophagitisSeok Hyung Kang0Myong Ki Baeg1Sun-Hye Ko2Hyunjung Hwang3Sang Yeop Yi4Sung Jin Moon5Jeongkeun Park6Division of Gastroenterology, Department of Internal Medicine, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, KoreaDivision of Gastroenterology, Department of Internal Medicine, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, KoreaDepartment of Internal Medicine, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, KoreaDivision of Gastroenterology, Department of Internal Medicine, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, KoreaDepartment of Pathology, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, KoreaDivision of Nephrology, Department of Internal Medicine, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, KoreaDepartment of Internal Medicine, International St. Mary’s Hospital, Catholic Kwandong University College of Medicine, Incheon, KoreaChest pain in kidney transplant patients is usually caused by cardiac or pulmonary problems. However, it may be rarely caused by opportunistic esophageal infections. A 66-year-old female kidney transplant recipient was admitted because of chest pain. She had been treated with high-dose steroid and immunosuppressants for acute T-cell-mediated rejection. Cardiologic and pulmonary evaluations had normal results. Endoscopic examination revealed three clear ulcerative lesions in the esophagus. Histological and immunohistochemical staining of the endoscopic biopsy specimens revealed coinfection of herpes simplex virus and cytomegalovirus. The patient was treated with intravenous ganciclovir for 2 weeks. Her symptoms completely resolved, and follow-up endoscopy revealed complete healing of the previous ulcers. Viral esophagitis should be considered in the differential diagnosis in kidney transplant recipients presenting with chest pain.http://helicojournal.org/upload/pdf/kjhugr-2019-19-1-61.pdfChest painCytomegalovirusEsophagitisHerpes simplex virusKidney transplantation
spellingShingle Seok Hyung Kang
Myong Ki Baeg
Sun-Hye Ko
Hyunjung Hwang
Sang Yeop Yi
Sung Jin Moon
Jeongkeun Park
Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Chest pain
Cytomegalovirus
Esophagitis
Herpes simplex virus
Kidney transplantation
title Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis
title_full Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis
title_fullStr Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis
title_full_unstemmed Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis
title_short Chest Pain in a Renal Transplant Recipient due to Concomitant Cytomegalovirus and Herpes Simplex Virus Esophagitis
title_sort chest pain in a renal transplant recipient due to concomitant cytomegalovirus and herpes simplex virus esophagitis
topic Chest pain
Cytomegalovirus
Esophagitis
Herpes simplex virus
Kidney transplantation
url http://helicojournal.org/upload/pdf/kjhugr-2019-19-1-61.pdf
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