Single-nucleus transcriptomic analysis reveals the regulatory circuitry of myofiber XBP1 during regenerative myogenesis

Summary: Endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) is activated in skeletal muscle under multiple conditions. However, the role of the UPR in the regulation of muscle regeneration remains less understood. We demonstrate that gene expression of various markers of the U...

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Bibliographic Details
Main Authors: Aniket S. Joshi, Micah B. Castillo, Meiricris Tomaz da Silva, Anh Tuan Vuong, Preethi H. Gunaratne, Radbod Darabi, Yu Liu, Ashok Kumar
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224025975
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