Mathematical modeling framework enhances clinical trial design for maintenance treatment in oncology

Abstract Clinical trials are costly and time-intensive endeavors, with a high rate of drug candidate failures. Moreover, the standard approaches often evaluate drugs under a limited number of protocols. In oncology, where multiple treatment protocols can yield divergent outcomes, addressing this iss...

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Bibliographic Details
Main Authors: Emilia Kozłowska, Ulla-Maija Haltia, Krzysztof Puszynski, Anniina Färkkilä
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-80768-6
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