Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations

Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations

Hepatitis B virus (HBV) DNA integration into the host cell genome is reportedly a major cause of liver cancer, and a source of hepatitis B surface antigen (HBsAg). High HBsAg levels can alter immune responses which therefore contributes to the progression of HBV-related disease. However, to what ext...

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Bibliographic Details
Main Authors: Dong Li, Vikki Ho, Chiao-Fang Teng, Hung-Wen Tsai, Yuanyuan Liu, Sarah Bae, Harout Ajoyan, Jochen M. Wettengel, Ulrike Protzer, Brian S. Gloss, Rebecca J. Rockett, Rafid Al Asady, Jane Li, Simon So, Jacob George, Mark W. Douglas, Thomas Tu
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
HBV DNA integration
functional cure
fine needle aspiration
digital droplet PCR
HBsAg
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2450025
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