Integrative analysis of multi-omics data identified PLG as key gene related to Anoikis resistance and immune phenotypes in hepatocellular carcinoma

Integrative analysis of multi-omics data identified PLG as key gene related to Anoikis resistance and immune phenotypes in hepatocellular carcinoma

Abstract Purpose The extracellular matrix (ECM) plays a pivotal role in the initiation and progression of hepatocellular carcinoma (HCC) by facilitating the proliferation of HCC cells and enabling resistance to Anoikis. ECM also provide structural support that aids in the invasion of HCC cells, ther...

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Bibliographic Details
Main Authors: Xueyan Wang, Lei Gao, Haiyuan Li, Yanling Ma, Bofang Wang, Baohong Gu, Xuemei Li, Lin Xiang, Yuping Bai, Chenhui Ma, Hao Chen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Anoikis resistance
Hepatocellular carcinoma
Immunotherapy
Multi-omics
Machine learning
Bioinformatics
Online Access:https://doi.org/10.1186/s12967-024-05858-5
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https://doi.org/10.1186/s12967-024-05858-5

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