CHD1L accelated the progression of cutaneous squamous cell carcinoma via promoting PI3K/PD-L1 signaling pathway induced M2 polarization of TAMs

CHD1L accelated the progression of cutaneous squamous cell carcinoma via promoting PI3K/PD-L1 signaling pathway induced M2 polarization of TAMs

Abstract To investigate CHD1L’s impacts and molecular processes in hypoxic cutaneous squamous cell carcinoma. Monoclonal proliferation assays and CCK-8 were used to detect the proliferation capacity of A431 cells and Colon16 cells; wound healing experiments and Transwell assays were used to examine...

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Bibliographic Details
Main Authors: Mei Liu, Chao Lv, Haiping Dong, Meng Zhou, Yao Yao, Huanrong Hu, Na Shen, Baoguo Liu, Guoying Miao, Yaling Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Cutaneous squamous cell carcinoma
Hypoxia
CHD1L
Tumor-associated macrophages
Online Access:https://doi.org/10.1038/s41598-024-82594-2
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https://doi.org/10.1038/s41598-024-82594-2

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