Tacrolimus: Physicochemical stability challenges, analytical methods, and new formulations

Tacrolimus, a potent immunosuppressant, is widely used in several formulations to treat organ rejection in transplant patients. However, its physicochemical stability poses significant challenges, including thermal instability, photostability issues, low solubility, and drug-excipient incompatibilit...

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Bibliographic Details
Main Authors: Sara Sajjadi, Ali Shayanfar, Farhad Kiafar, Mohammadreza Siahi-Shadbad
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156724000574
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