One-Pot Synthesis of Hydroxylated Alkaloids from Sugars via a Pictet–Spengler-Type Reaction

One-Pot Synthesis of Hydroxylated Alkaloids from Sugars via a Pictet–Spengler-Type Reaction

An efficient and convenient strategy has been successfully developed for the preparation of novel hydroxylated alkaloid derivatives (also called fused multicyclic iminosugars) from <i>p</i>-toluenesulfonylated sugars through a Pictet–Spengler-type mechanism. This method is highly stereos...

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Bibliographic Details
Main Authors: Likai Zhou, Na Ma, Jilai Wu, Weilin Yang, Lijing Feng, Song Xie, Lili Wang, Hua Chen
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
hydroxylated alkaloids
fused multicyclic iminosugars
Pictet–Spengler reaction
antitumor activity
Online Access:https://www.mdpi.com/1420-3049/29/23/5709
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