Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy

Natural killer cell engagers: From bi‐specific to tri‐specific and tetra‐specific engagers for enhanced cancer immunotherapy

Abstract Natural killer cell engagers (NKCEs) are a specialised subset of antibodies capable of simultaneously targeting endogenous NK cells and tumour cells, generating precise and effective cytolytic responses against cancer. This review systematically explores NK engagers as a rising star in NK‐m...

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Bibliographic Details
Main Authors: An Zhu, Yu Bai, Yanyang Nan, Dianwen Ju
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Clinical and Translational Medicine
Subjects:
bi‐specific NKCEs
cytokines
natural killer cell engagers
NK receptors
tetra‐specific NKCEs
tri‐specific NKCEs
Online Access:https://doi.org/10.1002/ctm2.70046
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https://doi.org/10.1002/ctm2.70046

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