Elucidating the role of CYFIP2 in conferring cisplatin resistance in esophageal squamous cell carcinoma

Elucidating the role of CYFIP2 in conferring cisplatin resistance in esophageal squamous cell carcinoma

Abstract Cisplatin (CDDP) serves as a vital component in the chemotherapeutic approach to treat esophageal squamous cell carcinoma (ESCC). However, prolonged CDDP application frequently culminates in resistance, compromising therapeutic outcomes. Through genome-wide CRISPR library screening, our stu...

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Bibliographic Details
Main Authors: Peipei Zhang, Weiguang Zhang, Zhinuan Hong, Junfei Jiang, Ningzi Wu, Jihong Lin, Mingqiang Kang
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Esophageal squamous cell carcinoma (ESCC)
Cisplatin
CRISPR library
CYFIP2
Online Access:https://doi.org/10.1038/s41598-024-77420-8
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https://doi.org/10.1038/s41598-024-77420-8

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