Exploring circulating cell-free DNA as a biomarker and as an inducer of AIM2-inflammasome-mediated inflammation in patients with abdominal aortic aneurysm

Abstract Circulating cell-free (cf) DNA in blood plasma is considered a diagnostic and prognostic biomarker of tissue damage and could be a driver of chronic inflammation by stimulating the innate immune response via activation of inflammasomes. Increased AIM2-inflammasome activity in the aortic wal...

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Bibliographic Details
Main Authors: Susanne Dihlmann, Carolin Kaduk, Karola H. Passek, Anja Spieler, Dittmar Böckler, Andreas S. Peters
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-06220-5
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