siRNA Treatment Enhances Collagen Fiber Formation in Tissue-Engineered Meniscus via Transient Inhibition of Aggrecan Production

The complex collagen network of the native meniscus and the gradient of the density and alignment of this network through the meniscal enthesis is essential for the proper mechanical function of these tissues. This architecture is difficult to recapitulate in tissue-engineered replacement strategies...

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Bibliographic Details
Main Authors: Serafina G. Lopez, Lara A. Estroff, Lawrence J. Bonassar
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
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Online Access:https://www.mdpi.com/2306-5354/11/12/1308
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