Knockdown of CSF1R molecules enhances the antitumor effects of CD8+ T lymphocytes in bladder cancer

Knockdown of CSF1R molecules enhances the antitumor effects of CD8+ T lymphocytes in bladder cancer

Abstract Objective In this study, we preliminarily investigated the efffects of the colony stimulating factor 1 receptor (CSF1R) molecules on CD8+ T cells in bladder cancer (BLCA) and the underlying molecular mechanism. Methods The effects of CSF1R in CD8+ T cells on BLCA cell proliferation, migrati...

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Bibliographic Details
Main Authors: Jingxuan Peng, Dongjie Li, Boyu Xiang, Zhongyi Li, Zhengyan Tang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
Subjects:
CSF1R
CD8+ T cells
Bladder cancer
Immune
Online Access:https://doi.org/10.1007/s12672-025-03244-1
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