Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors
The incidence of mammary gland tumors in dogs is a significant issue, characterized by notable rates of malignancy, recurrence, and disease burden. However, the lack of comprehensive information and correlated studies has presented challenges in establishing an effective surgical treatment strategy....
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Animals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2615/14/24/3687 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1846106208890519552 |
|---|---|
| author | Seung-Hyun Kim Dae Sung Yoo Chul-Ho Park Sang-Ho Lee Ju-Hwan Lee Taeho Ahn Bock-Gie Jung Jun-Gyu Park Sang-Ik Park Chun-Sik Bae |
| author_facet | Seung-Hyun Kim Dae Sung Yoo Chul-Ho Park Sang-Ho Lee Ju-Hwan Lee Taeho Ahn Bock-Gie Jung Jun-Gyu Park Sang-Ik Park Chun-Sik Bae |
| author_sort | Seung-Hyun Kim |
| collection | DOAJ |
| description | The incidence of mammary gland tumors in dogs is a significant issue, characterized by notable rates of malignancy, recurrence, and disease burden. However, the lack of comprehensive information and correlated studies has presented challenges in establishing an effective surgical treatment strategy. In this study, a cohort of 95 dogs diagnosed with mammary tumors underwent evaluation using various surgical methods, medications, ovariohysterectomy, and assessments of margin completeness to analyze clinical outcomes. Significant clinical outcomes were observed following radical mastectomy and conservative surgeries, irrespective of TNM stages and histopathological grade of malignancy. Complete excision demonstrated significantly improved survival time and disease-free interval compared to incomplete excision. It is noted that complete surgical excision provides benefits, even in cases where lymphatic invasion is present. However, further investigations are necessary to validate the clinical results and mitigate side effects from radical mastectomy. Despite postoperative complications, several studies continue to advocate for more radical mastectomies due to their favorable risk-benefit ratio. Moreover, advanced inpatient treatments can now effectively manage or mitigate many of these complications. This study emphasizes the critical role of surgical proficiency and postoperative medication in treating malignant mammary tumors in dogs, and it provides insights that may contribute to the development of more effective treatment strategies for this condition. |
| format | Article |
| id | doaj-art-6df68642e6f64abeb7af40d51f1ed448 |
| institution | Kabale University |
| issn | 2076-2615 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj-art-6df68642e6f64abeb7af40d51f1ed4482024-12-27T14:05:55ZengMDPI AGAnimals2076-26152024-12-011424368710.3390/ani14243687Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary TumorsSeung-Hyun Kim0Dae Sung Yoo1Chul-Ho Park2Sang-Ho Lee3Ju-Hwan Lee4Taeho Ahn5Bock-Gie Jung6Jun-Gyu Park7Sang-Ik Park8Chun-Sik Bae9Department of Veterinary Surgery, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaSuncheon Bay Animal Hospital, Suncheon-si 58016, Republic of Korea4rest Animal Medical Center, Jeonju-si 54828, Republic of KoreaCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaCollege of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaDepartment of Veterinary Microbiology, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaDepartment of Veterinary Zoonotic Diseases, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaDepartment of Veterinary Pathology, College of Veterinary Medicine and BK21 FOUR Program, Chonnam National University, Gwangju 61186, Republic of KoreaDepartment of Veterinary Surgery, College of Veterinary Medicine, Chonnam National University, Gwangju 61186, Republic of KoreaThe incidence of mammary gland tumors in dogs is a significant issue, characterized by notable rates of malignancy, recurrence, and disease burden. However, the lack of comprehensive information and correlated studies has presented challenges in establishing an effective surgical treatment strategy. In this study, a cohort of 95 dogs diagnosed with mammary tumors underwent evaluation using various surgical methods, medications, ovariohysterectomy, and assessments of margin completeness to analyze clinical outcomes. Significant clinical outcomes were observed following radical mastectomy and conservative surgeries, irrespective of TNM stages and histopathological grade of malignancy. Complete excision demonstrated significantly improved survival time and disease-free interval compared to incomplete excision. It is noted that complete surgical excision provides benefits, even in cases where lymphatic invasion is present. However, further investigations are necessary to validate the clinical results and mitigate side effects from radical mastectomy. Despite postoperative complications, several studies continue to advocate for more radical mastectomies due to their favorable risk-benefit ratio. Moreover, advanced inpatient treatments can now effectively manage or mitigate many of these complications. This study emphasizes the critical role of surgical proficiency and postoperative medication in treating malignant mammary tumors in dogs, and it provides insights that may contribute to the development of more effective treatment strategies for this condition.https://www.mdpi.com/2076-2615/14/24/3687canine mammary gland tumorscomplete excisionradical mastectomysurvival timedisease-free interval |
| spellingShingle | Seung-Hyun Kim Dae Sung Yoo Chul-Ho Park Sang-Ho Lee Ju-Hwan Lee Taeho Ahn Bock-Gie Jung Jun-Gyu Park Sang-Ik Park Chun-Sik Bae Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors Animals canine mammary gland tumors complete excision radical mastectomy survival time disease-free interval |
| title | Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors |
| title_full | Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors |
| title_fullStr | Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors |
| title_full_unstemmed | Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors |
| title_short | Radical Mastectomy Efficiently Improves Long-Term Clinical Outcomes in Dogs with Malignant Mammary Tumors |
| title_sort | radical mastectomy efficiently improves long term clinical outcomes in dogs with malignant mammary tumors |
| topic | canine mammary gland tumors complete excision radical mastectomy survival time disease-free interval |
| url | https://www.mdpi.com/2076-2615/14/24/3687 |
| work_keys_str_mv | AT seunghyunkim radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT daesungyoo radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT chulhopark radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT sangholee radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT juhwanlee radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT taehoahn radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT bockgiejung radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT jungyupark radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT sangikpark radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors AT chunsikbae radicalmastectomyefficientlyimproveslongtermclinicaloutcomesindogswithmalignantmammarytumors |