Unveiling the immune microenvironment of complex tissues and tumors in transcriptomics through a deconvolution approach

Unveiling the immune microenvironment of complex tissues and tumors in transcriptomics through a deconvolution approach

Abstract Accurately resolving the composition of tumor-infiltrating leukocytes is pivotal for advancing cancer immunotherapy strategies. Despite the success of some clinical trials, applying these strategies remains limited due to the challenges in deciphering the immune microenvironment. In this st...

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Bibliographic Details
Main Authors: Shu-Hwa Chen, Bo-Yi Yu, Wen-Yu Kuo, Ya-Bo Lin, Sheng-Yao Su, Wei-Hsuan Chuang, I.-Hsuan Lu, Chung-Yen Lin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
Cancer
Immunotherapy
Deconvolution
Alpha diversity
Beta diversity
Precision medicine
Online Access:https://doi.org/10.1186/s12885-025-14089-w
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https://doi.org/10.1186/s12885-025-14089-w

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