Targeting TSPEAR-AS2 suppresses tumor growth and interferon signaling in esophageal cancer

Abstract Dysregulation of long non-coding RNAs (lncRNAs) and interferon signaling contributes to tumorigenesis and progression; however, their crosstalk in tumor biology remains poorly understood. Here, we showed that TSPEAR-AS2, an lncRNA mediated by METTL1, activates the interferon signaling pathw...

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Bibliographic Details
Main Authors: Chunyan Zhang, Yuanbo Cui
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-80439-6
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