Prognostic Value of GPNMB, EGFR, p-PI3K, and Ki-67 in Patients with Esophageal Squamous Cell Carcinoma

Prognostic Value of GPNMB, EGFR, p-PI3K, and Ki-67 in Patients with Esophageal Squamous Cell Carcinoma

Background. GPNMB is a newly discovered tumour-promoting factor that may promote tumour cell progression by activating the PI3K/AKT pathway by EGFR. However, there are insufficient studies about GPNMB in ESCC. This study investigated the relationship between GPNMB and EGFR/PI3K pathway genes in ESCC...

Full description

Saved in:

Bibliographic Details
Main Authors:	Bo Wang, Mengyan Li, Anna Su, Yongmei Gao, Yan Shi, Chao Li, Wenying Liu, Liping Su, Wan Li, Yuqing Ma
Format:	Article
Language:	English
Published:	Wiley 2022-01-01
Series:	Analytical Cellular Pathology
Online Access:	http://dx.doi.org/10.1155/2022/9303081
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Comment on “PCNA and Ki67: Prognostic proliferation markers for oral cancer”
by: Muthupandian Saravanan
Published: (2024-06-01)

Immunoexpression of P16 and Ki 67 in oral squamous cell carcinoma: Association with clinicopathological parameters.
by: Shadan Mohamad Omer, et al.
Published: (2020-12-01)

Correlation between Ki-67 labeling index and mitotic index in Head and neck squamous cell carcinoma
by: Das C. K Deepa, et al.
Published: (2024-12-01)

PCNA, Ki-67, p53, bcl-2 and Prognosis in Intraoral Squamous Cell Carcinoma of the Head and Neck
by: Karin Nylander, et al.
Published: (1997-01-01)

Prognostic relevance of Ki-67 and P16/INK4a markers in histological diagnosis of cervical dysplasia
by: T. A. Dimitriadi, et al.
Published: (2020-03-01)

Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence
by: Wang Wenhui, et al.
Published: (2024-12-01)

Integrating traditional biomarkers and emerging predictors to assess neoadjuvant chemotherapy efficacy in breast cancer: a multifactorial analysis of Ki-67, CDK4, EGFR, TILs and ctDNA
by: Tianzhao Du, et al.
Published: (2024-12-01)

The importance of Ki-67 proliferation index in small cell lung cancer
by: Seda Beyhan Sağmen, et al.
Published: (2025-01-01)

Multi-institutional evaluation comparing guidance from International Ki67 Working Group vs National Health Commission of China on immunohistochemistry-based Ki67 assessment alongside the Quantitative Dot Blot method
by: Yin Wang, et al.
Published: (2025-01-01)

MSC-sEVs exacerbate senescence by transferring bisecting GlcNAcylated GPNMB
by: Yihan Ma, et al.
Published: (2025-01-01)

Comparative Study of Gleason 7 (3+4) and (4+3) Prostatic Adenocarcinomas with Prognostic Criteria and Immunohistochemical Profiles of AMACR, PSA and Ki-67
by: Clarice F. E. M. Osório, et al.
Published: (2025-01-01)

Assessment of Ki-67 expression in cases of prostatic carcinoma and its correlation with clinical outcomes
by: Sumaira Siddiqui
Published: (2024-04-01)

The Impact of p53 and Ki67 Expression in Endometrial Cancer and its Effect on Survival
by: Zekiye Sahin, et al.
Published: (2022-03-01)

Ki-67 and CDK1 control the dynamic association of nuclear lipids with mitotic chromosomes
by: Hsiao-Tang Hu, et al.
Published: (2025-01-01)

Study of the association of the known prognostic variables with EGFR expression in head and neck squamous cell carcinomas
by: Toyaja Jadhav, et al.
Published: (2023-07-01)

The value of multiparametric MRI radiomics and machine learning in predicting preoperative Ki-67 expression level in breast cancer
by: Yan Lu, et al.
Published: (2025-01-01)

Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model
by: Jan P. A. Baak, et al.
Published: (2005-01-01)

Clinicopathological importance of immunohistochemical expression of OCT4, c-MYC and Ki-67 in colorectal cancer
by: Rabia Hursitoglu, et al.
Published: (2024-12-01)

Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model
by: Rosella Silvestrini
Published: (2005-01-01)

Ki67 Predicts Progression in Early CIN: Validation of a Multivariate Progression-Risk Model
by: Arnold-Jan Kruse, et al.
Published: (2004-01-01)

Potential value of novel multiparametric MRI radiomics for preoperative prediction of microsatellite instability and Ki-67 expression in endometrial cancer
by: Zhichao Wang, et al.
Published: (2025-01-01)

Synovial sarcoma. Evaluation of Prognosis with Emphasis on the Study of DNA Ploidy and Proliferation (PCNA and Ki-67) Markers
by: José M. Lopes, et al.
Published: (1998-01-01)

H. Wendl Leaf Metabolites Potentiate the Radiosensitivity of Hepatocellular Carcinoma Through Ki67 and PARP Inhibition
by: Nabil M. Selim PhD, et al.
Published: (2025-01-01)

Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma
by: John Davies, et al.
Published: (2012-01-01)

Ｋｉ－６７在木村病患者中的表达和复发相关因素分析
Published: (2014-01-01)

Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67
by: Rende Peng, et al.
Published: (2025-01-01)

A multi-modal deep learning model for prediction of Ki-67 for meningiomas using pretreatment MR images
by: Chaoyue Chen, et al.
Published: (2025-01-01)

Does altered Ki67 expression in recurrent membranous basal cell adenoma point toward the need for reclassification?
by: Dhinakaran Paranchodi, et al.
Published: (2024-09-01)

A novel sensitizer reduces EGFR-TKI resistance by regulating the PI3K/Akt/mTOR pathway and autophagy
by: Jue Zhang, et al.
Published: (2025-01-01)

The Role of EGFR/PI3K/Akt/cyclinD1 Signaling Pathway in Acquired Middle Ear Cholesteatoma
by: Wei Liu, et al.
Published: (2013-01-01)

Prognostic role of the pathological status following neoadjuvant chemoradiotherapy and surgery in esophageal squamous cell carcinoma
by: Xiaofeng Duan, et al.
Published: (2025-01-01)

Prognostic value of immunosuppression scores in patients with esophageal squamous cell carcinoma: a multicenter study
by: Shao-jun Xu, et al.
Published: (2025-01-01)

Study of morphology with assessment of expression of proliferation marker Ki67 antigen and P53 protein in lesions of gall bladder
by: Ojasvi Ramesh, et al.
Published: (2024-04-01)

Comparison of the Manual, Semiautomatic, and Automatic Selection and Leveling of Hot Spots in Whole Slide Images for Ki-67 Quantification in Meningiomas
by: Zaneta Swiderska, et al.
Published: (2015-01-01)

Prediction of Ki-67 expression in gastric gastrointestinal stromal tumors using histogram analysis of monochromatic and iodine images derived from spectral CT
by: Xianwang Liu, et al.
Published: (2024-12-01)

Sporoderm-Removed Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway
by: Jingyan Liu Master degree, et al.
Published: (2021-11-01)

Prognostic value of tumor‐infiltrating lymphocytes and PD‐L1 expression in esophageal squamous cell carcinoma
by: Jie Hu, et al.
Published: (2024-09-01)

Inmunolocalización de citoqueratina 14, 19 y Ki-67 en el epitelio de pacientes con agrandamiento gingival
by: Víctor Simancas-Escorcia, et al.
Published: (2023-01-01)

Stromal Expression of CD10 in Invasive Breast Carcinoma and Its Correlation with ER, PR, HER2-neu, and Ki67
by: Vandana Puri, et al.
Published: (2011-01-01)

Predicting of Ki-67 Expression Level Using Diffusion-Weighted and Synthetic Magnetic Resonance Imaging in Invasive Ductal Breast Cancer
by: Liying Zhang, et al.
Published: (2023-01-01)