LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis

LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis

BackgroundMacrophage polarization plays a pivotal role in shaping the tumor microenvironment and influencing cancer progression. Long non-coding RNAs (lncRNAs) have emerged as important regulators of this process. This study investigated the role of lncRNA OIP5-AS1 in lung adenocarcinoma (LUAD) prog...

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Bibliographic Details
Main Authors: Yihan Liu, Yuhua Wang, Long Cui, Runze Li, Dan Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
macrophage polarization
OIP5-AS1
miR-429
DOCK4
lung adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1569644/full
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