Dehydrocostus lactone suppresses gastric cancer progression by targeting ACLY to inhibit fatty acid synthesis and autophagic flux

Introduction: Dehydrocostus lactone (Dehy), a natural sesquiterpene lactone from Saussurea lappa Clarke, displays remarkable efficacy in treating cancer and gastrointestinal disorders. However, its anti-gastric cancer (GC) effect remains poorly understood. Objectives: Our study aimed to elucidate th...

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Bibliographic Details
Main Authors: Yuxuan Chen, Junyu Shen, Mengyun Yuan, Huaizhi Li, Yaqi Li, Shanshan Zheng, Bo Han, Cancan Zhang, Shenlin Liu, Qingmin Sun, Jian Wu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Advanced Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2090123224000407
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