Cyclosporin A alleviates influenza A (H1N1) virus-induced chronic pulmonary inflammation through decreasing IFN-γ-producing T lymphocytes

Cyclosporin A alleviates influenza A (H1N1) virus-induced chronic pulmonary inflammation through decreasing IFN-γ-producing T lymphocytes

Abstract Influenza causes 3–5 million severe cases globally each year, with severe viral pneumonia often requiring hospitalization for over four weeks. While the inflammatory response to influenza infection helps control viral replication, excessive inflammation is a key driver of disease severity a...

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Bibliographic Details
Main Authors: Wenbin Ding, Xin Zhao, Zhengyang Lin, Mengxi Luo, Nanshan Zhong, Kefang Lai, Zheng Deng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Virology Journal
Subjects:
Cyclosporin A
Influenza A virus
Lymphocytes
Chronic pulmonary inflammation
Interferon-γ
Online Access:https://doi.org/10.1186/s12985-025-02887-4
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https://doi.org/10.1186/s12985-025-02887-4

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