Structure-Activity Relationship for Fe(III)-Salen-Like Complexes as Potent Anticancer Agents

Quantitative structure activity relationship (QSAR) for the anticancer activity of Fe(III)-salen and salen-like complexes was studied. The methods of density function theory (B3LYP/LANL2DZ) were used to optimize the structures. A pool of descriptors was calculated: 1497 theoretical descriptors and...

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Bibliographic Details
Main Authors: Zahra Ghanbari, Mohammad R. Housaindokht, Mohammad Izadyar, Mohammad R. Bozorgmehr, Hossein Eshtiagh-Hosseini, Ahmad R. Bahrami, Maryam M. Matin, Maliheh Javan Khoshkholgh
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/745649
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