Pyrazolo[1,5-a]pyrimidin-7-ones as promising antimicrobial scaffolds: In vitro and in vivo evaluation.
This study presents a family of pyrazolo[1,5-a]pyrimidin-7-ones as potential antimicrobial agents. Initial screening against Staphylococcus aureus, Escherichia coli, and Candida albicans identified compound 3 as active against S. aureus (MIC₅₀ 1.8 μM). A structure activity relationship study of 35 a...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-07-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625003868 |
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