Signatures of omicron-like adaptation in early SARS-CoV-2 variants and chronic infection

Signatures of omicron-like adaptation in early SARS-CoV-2 variants and chronic infection

Summary: Persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are a source of new variants and can provide insight into evolutionary trajectories. Here, we observe upper airway-specific evolution of SARS-CoV-2, demonstrating a fusion peptide (FP) domain mutation (S:P812...

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Main Authors: Mark Tsz Kin Cheng, Mazharul Altaf, Jesu Castin, Ann-Kathrin Reuschl, Benjamin L. Sievers, Kimia Kamelian, Dejan Mesner, Rebecca B. Morse, Adam Abdullahi, Bo Meng, Kata Csiba, Steven A. Kemp, Darren P. Martin, Clare Jolly, Christopher Ruis, Lipi Thukral, Ravindra K. Gupta
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725009064
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