Severe Acute Hepatitis B Treated with Entecavir

Hepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical an...

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Main Authors: Giuseppe Vittorio Luigi De Socio, Alessio Sgrelli, Andrea Tosti, Franco Baldelli
Format: Article
Language:English
Published: PAGEPress Publications 2011-03-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
Subjects:
Online Access:http://www.mjhid.org/index.php/mjhid/article/view/316
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author Giuseppe Vittorio Luigi De Socio
Alessio Sgrelli
Andrea Tosti
Franco Baldelli
author_facet Giuseppe Vittorio Luigi De Socio
Alessio Sgrelli
Andrea Tosti
Franco Baldelli
author_sort Giuseppe Vittorio Luigi De Socio
collection DOAJ
description Hepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical and hepatic function. The patient was treated with entecavir without critical side effects. We observed rapid clinical and laboratory improvements and the disappearance of surface antigen (HBsAg). The treatment with entecavir was protracted until 17th week when the antibody antiHBs (anti HBs) appeared. Entecavir should be carefully considered for the treatment of severe acute hepatitis B cases.
format Article
id doaj-art-6bb4fe9d49f74c89aa9f1fc51feaa1d0
institution Kabale University
issn 2035-3006
language English
publishDate 2011-03-01
publisher PAGEPress Publications
record_format Article
series Mediterranean Journal of Hematology and Infectious Diseases
spelling doaj-art-6bb4fe9d49f74c89aa9f1fc51feaa1d02024-12-02T03:09:42ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062011-03-0131e2011010e201101010.4084/mjhid.2011.010208Severe Acute Hepatitis B Treated with EntecavirGiuseppe Vittorio Luigi De Socio0Alessio Sgrelli1Andrea Tosti2Franco Baldelli3Clinica di Malattie Infettive, Azienda ospedaliera di PerugiaClinica di Malattie Infettive, Università di PerugiaClinica di Malattie Infettive, Azienda ospedaliera di PerugiaClinica di Malattie Infettive, Università di PerugiaHepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical and hepatic function. The patient was treated with entecavir without critical side effects. We observed rapid clinical and laboratory improvements and the disappearance of surface antigen (HBsAg). The treatment with entecavir was protracted until 17th week when the antibody antiHBs (anti HBs) appeared. Entecavir should be carefully considered for the treatment of severe acute hepatitis B cases.http://www.mjhid.org/index.php/mjhid/article/view/316Acute Hepatitis B, Entecavir, HBV therapy
spellingShingle Giuseppe Vittorio Luigi De Socio
Alessio Sgrelli
Andrea Tosti
Franco Baldelli
Severe Acute Hepatitis B Treated with Entecavir
Mediterranean Journal of Hematology and Infectious Diseases
Acute Hepatitis B, Entecavir, HBV therapy
title Severe Acute Hepatitis B Treated with Entecavir
title_full Severe Acute Hepatitis B Treated with Entecavir
title_fullStr Severe Acute Hepatitis B Treated with Entecavir
title_full_unstemmed Severe Acute Hepatitis B Treated with Entecavir
title_short Severe Acute Hepatitis B Treated with Entecavir
title_sort severe acute hepatitis b treated with entecavir
topic Acute Hepatitis B, Entecavir, HBV therapy
url http://www.mjhid.org/index.php/mjhid/article/view/316
work_keys_str_mv AT giuseppevittorioluigidesocio severeacutehepatitisbtreatedwithentecavir
AT alessiosgrelli severeacutehepatitisbtreatedwithentecavir
AT andreatosti severeacutehepatitisbtreatedwithentecavir
AT francobaldelli severeacutehepatitisbtreatedwithentecavir