Severe Acute Hepatitis B Treated with Entecavir
Hepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical an...
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Language: | English |
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PAGEPress Publications
2011-03-01
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Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/316 |
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author | Giuseppe Vittorio Luigi De Socio Alessio Sgrelli Andrea Tosti Franco Baldelli |
author_facet | Giuseppe Vittorio Luigi De Socio Alessio Sgrelli Andrea Tosti Franco Baldelli |
author_sort | Giuseppe Vittorio Luigi De Socio |
collection | DOAJ |
description | Hepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical and hepatic function. The patient was treated with entecavir without critical side effects. We observed rapid clinical and laboratory improvements and the disappearance of surface antigen (HBsAg). The treatment with entecavir was protracted until 17th week when the antibody antiHBs (anti HBs) appeared. Entecavir should be carefully considered for the treatment of severe acute hepatitis B cases. |
format | Article |
id | doaj-art-6bb4fe9d49f74c89aa9f1fc51feaa1d0 |
institution | Kabale University |
issn | 2035-3006 |
language | English |
publishDate | 2011-03-01 |
publisher | PAGEPress Publications |
record_format | Article |
series | Mediterranean Journal of Hematology and Infectious Diseases |
spelling | doaj-art-6bb4fe9d49f74c89aa9f1fc51feaa1d02024-12-02T03:09:42ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062011-03-0131e2011010e201101010.4084/mjhid.2011.010208Severe Acute Hepatitis B Treated with EntecavirGiuseppe Vittorio Luigi De Socio0Alessio Sgrelli1Andrea Tosti2Franco Baldelli3Clinica di Malattie Infettive, Azienda ospedaliera di PerugiaClinica di Malattie Infettive, Università di PerugiaClinica di Malattie Infettive, Azienda ospedaliera di PerugiaClinica di Malattie Infettive, Università di PerugiaHepatitis B virus (HBV) infection constitutes a serious global health problem. Nowadays there are divergent data regarding the use of antiviral drugs to treat acute hepatitis B. We present here a case of a 62-year-old man affected by severe acute hepatitis B with progressive worsening of clinical and hepatic function. The patient was treated with entecavir without critical side effects. We observed rapid clinical and laboratory improvements and the disappearance of surface antigen (HBsAg). The treatment with entecavir was protracted until 17th week when the antibody antiHBs (anti HBs) appeared. Entecavir should be carefully considered for the treatment of severe acute hepatitis B cases.http://www.mjhid.org/index.php/mjhid/article/view/316Acute Hepatitis B, Entecavir, HBV therapy |
spellingShingle | Giuseppe Vittorio Luigi De Socio Alessio Sgrelli Andrea Tosti Franco Baldelli Severe Acute Hepatitis B Treated with Entecavir Mediterranean Journal of Hematology and Infectious Diseases Acute Hepatitis B, Entecavir, HBV therapy |
title | Severe Acute Hepatitis B Treated with Entecavir |
title_full | Severe Acute Hepatitis B Treated with Entecavir |
title_fullStr | Severe Acute Hepatitis B Treated with Entecavir |
title_full_unstemmed | Severe Acute Hepatitis B Treated with Entecavir |
title_short | Severe Acute Hepatitis B Treated with Entecavir |
title_sort | severe acute hepatitis b treated with entecavir |
topic | Acute Hepatitis B, Entecavir, HBV therapy |
url | http://www.mjhid.org/index.php/mjhid/article/view/316 |
work_keys_str_mv | AT giuseppevittorioluigidesocio severeacutehepatitisbtreatedwithentecavir AT alessiosgrelli severeacutehepatitisbtreatedwithentecavir AT andreatosti severeacutehepatitisbtreatedwithentecavir AT francobaldelli severeacutehepatitisbtreatedwithentecavir |