Exploring distinct modes of inter-spike cross-linking for enhanced neutralization by SARS-CoV-2 antibodies

Exploring distinct modes of inter-spike cross-linking for enhanced neutralization by SARS-CoV-2 antibodies

Abstract The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its Omicron subvariants drastically amplifies transmissibility, infectivity, and immune escape, mainly due to their resistance to most neutralizing antibodies. Thus, exploring the mechanisms underlying antibod...

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Main Authors: Xuanyu Nan, Yujie Li, Rui Zhang, Ruoke Wang, Niannian Lv, Jiayi Li, Yuanfang Chen, Bini Zhou, Yangjunqi Wang, Ziyi Wang, Jiayi Zhu, Jing Chen, Jinqian Li, Wenlong Chen, Qi Zhang, Xuanling Shi, Changwen Zhao, Chunying Chen, Zhihua Liu, Yuliang Zhao, Dongsheng Liu, Xinquan Wang, Li-Tang Yan, Taisheng Li, Linqi Zhang, Yuhe R. Yang
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54746-5
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https://doi.org/10.1038/s41467-024-54746-5

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