Protective Role of Cepharanthine Against Equid Herpesvirus Type 8 Through AMPK and Nrf2/HO-1 Pathway Activation

Protective Role of Cepharanthine Against Equid Herpesvirus Type 8 Through AMPK and Nrf2/HO-1 Pathway Activation

Equid herpesvirus type 8 (EqHV-8) is known to cause respiratory disease and miscarriage in horses and donkeys, which is a major problem for the equine farming industry. However, there are currently limited vaccines or drugs available to effectively treat EqHV-8 infection. Therefore, it is crucial to...

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Bibliographic Details
Main Authors: Shuwen Li, Liangliang Li, Yijia Sun, Muhammad Zahoor Khan, Yue Yu, Lian Ruan, Li Chen, Juan Zhao, Junchi Jia, Yubao Li, Changfa Wang, Tongtong Wang
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
Subjects:
cepharanthine
oxidative stress
EqHV-8
antiviral activity
AMPK/Nrf2/HO-1 signaling pathway
Online Access:https://www.mdpi.com/1999-4915/16/11/1765
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