Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis

Abstract Background and aims The care needs of patients with Crohn’s disease (CD) may be heterogeneous. This study aimed to explore the latent class of care needs of patients with CD and differences in their characteristics and to analyze the factors influencing the different latent classes. Methods...

Full description

Saved in:
Bibliographic Details
Main Authors: Rongfei Duan, Wan Mei, Ming Lei, Danlei Chen, Ting Pan, Fang Kong, Yan Chen
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Gastroenterology
Subjects:
Online Access:https://doi.org/10.1186/s12876-025-03953-5
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849335757212221440
author Rongfei Duan
Wan Mei
Ming Lei
Danlei Chen
Ting Pan
Fang Kong
Yan Chen
author_facet Rongfei Duan
Wan Mei
Ming Lei
Danlei Chen
Ting Pan
Fang Kong
Yan Chen
author_sort Rongfei Duan
collection DOAJ
description Abstract Background and aims The care needs of patients with Crohn’s disease (CD) may be heterogeneous. This study aimed to explore the latent class of care needs of patients with CD and differences in their characteristics and to analyze the factors influencing the different latent classes. Methods A convenience sampling method was used to select 250 patients with CD who attended a tertiary-level hospital in Nanjing from August to November 2024 for the study. They were surveyed via the General Information Questionnaire, the Crohn’s Disease Care Needs Scale (CD-CNS), the Inflammatory Bowel Disease (IBD) Patient Symptom Clusters Assessment Scale, the Family Adaptability and Cohesion Scale (FACES), and the Post-traumatic Growth Inventory (PTGI). The latent classes of care needs of CD patients were identified via latent profile analysis (LPA), and the factors influencing their latent classes were analyzed via multiple logistic regression analyses. Results (1) The LPA results revealed that the care needs of CD patients were divided into three profiles as the best model fitting indicators: the “low-care-needs-adaptation group” (n = 96, 38.4%), the “moderate-care-needs-growth group” (n = 81, 32.4%), and the “high-care-needs-distress group” (n = 73, 29.2%). (2) Regression analyses revealed that current disease status, the presence of a stoma, symptom burden, family adaptability and cohesion, and post-traumatic growth (PTG) were influential factors in different latent classes. Conclusion There is significant heterogeneity in the care needs of CD patients. Care needs to focus on patients with high care needs and enhance their symptom management and psychological interventions to improve their PTG and reduce their disease burden.
format Article
id doaj-art-6b3ee9c111da4f73a5c0097007b95cec
institution Kabale University
issn 1471-230X
language English
publishDate 2025-05-01
publisher BMC
record_format Article
series BMC Gastroenterology
spelling doaj-art-6b3ee9c111da4f73a5c0097007b95cec2025-08-20T03:45:10ZengBMCBMC Gastroenterology1471-230X2025-05-0125111510.1186/s12876-025-03953-5Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysisRongfei Duan0Wan Mei1Ming Lei2Danlei Chen3Ting Pan4Fang Kong5Yan Chen6School of Nursing, Nanjing University of Chinese MedicineSchool of Nursing, Nanjing University of Chinese MedicineJiangsu Health Vocational CollegeSchool of Nursing, Nanjing University of Chinese MedicineSchool of Nursing, Nanjing University of Chinese MedicineGastroenterological Disease Diagnosis and Treatment Centre, The Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese MedicineDepartment of Nursing, The Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese MedicineAbstract Background and aims The care needs of patients with Crohn’s disease (CD) may be heterogeneous. This study aimed to explore the latent class of care needs of patients with CD and differences in their characteristics and to analyze the factors influencing the different latent classes. Methods A convenience sampling method was used to select 250 patients with CD who attended a tertiary-level hospital in Nanjing from August to November 2024 for the study. They were surveyed via the General Information Questionnaire, the Crohn’s Disease Care Needs Scale (CD-CNS), the Inflammatory Bowel Disease (IBD) Patient Symptom Clusters Assessment Scale, the Family Adaptability and Cohesion Scale (FACES), and the Post-traumatic Growth Inventory (PTGI). The latent classes of care needs of CD patients were identified via latent profile analysis (LPA), and the factors influencing their latent classes were analyzed via multiple logistic regression analyses. Results (1) The LPA results revealed that the care needs of CD patients were divided into three profiles as the best model fitting indicators: the “low-care-needs-adaptation group” (n = 96, 38.4%), the “moderate-care-needs-growth group” (n = 81, 32.4%), and the “high-care-needs-distress group” (n = 73, 29.2%). (2) Regression analyses revealed that current disease status, the presence of a stoma, symptom burden, family adaptability and cohesion, and post-traumatic growth (PTG) were influential factors in different latent classes. Conclusion There is significant heterogeneity in the care needs of CD patients. Care needs to focus on patients with high care needs and enhance their symptom management and psychological interventions to improve their PTG and reduce their disease burden.https://doi.org/10.1186/s12876-025-03953-5Crohn’s diseaseCare needsSymptom clustersLatent profile analysisPost-traumatic growthFamily adaptability
spellingShingle Rongfei Duan
Wan Mei
Ming Lei
Danlei Chen
Ting Pan
Fang Kong
Yan Chen
Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis
BMC Gastroenterology
Crohn’s disease
Care needs
Symptom clusters
Latent profile analysis
Post-traumatic growth
Family adaptability
title Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis
title_full Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis
title_fullStr Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis
title_full_unstemmed Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis
title_short Care needs profiles of Crohn’s disease patients and their associations with symptom clusters, post-traumatic growth, and family function: a latent profile analysis
title_sort care needs profiles of crohn s disease patients and their associations with symptom clusters post traumatic growth and family function a latent profile analysis
topic Crohn’s disease
Care needs
Symptom clusters
Latent profile analysis
Post-traumatic growth
Family adaptability
url https://doi.org/10.1186/s12876-025-03953-5
work_keys_str_mv AT rongfeiduan careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis
AT wanmei careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis
AT minglei careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis
AT danleichen careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis
AT tingpan careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis
AT fangkong careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis
AT yanchen careneedsprofilesofcrohnsdiseasepatientsandtheirassociationswithsymptomclustersposttraumaticgrowthandfamilyfunctionalatentprofileanalysis