Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes

Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes

Ethnopharmacological relevanceMenopausal syndrome (MPS) is a symptom of physical and psychosomatic abnormalities that women may face around the time of menopause. Hot flashes are the main symptom. Paeonia lactiflora extract (PLE) is the active ingredient extracted from Radix Paeonia alba. It can be...

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Bibliographic Details
Main Authors: Weilin Cui, Tingting Song, Dongmei Gao, Xiaoyu Wang, Ya Sun, Liyu Fu, Yichao Han, Jieqiong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
paeonia lactiflora extract
menopausal syndrome
transcriptomics
hypothalamus
hot flashes
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1587885/full
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