Orally delivered biodegradable targeted inflammation resolving pectin-coated nanoparticles induce anastomotic healing post intestinal surgery

Orally delivered biodegradable targeted inflammation resolving pectin-coated nanoparticles induce anastomotic healing post intestinal surgery

Abstract Targeted perioperative therapeutics supporting anastomotic healing during colitis are an urgent medical need. This study aimed to develop and evaluate a novel nanoparticle (NP)-based drug delivery system for improving anastomotic healing in Inflammatory bowel disease (IBD) patients followin...

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Bibliographic Details
Main Authors: Jong Hyun Lee, Stefan Reischl, Robert Leon Walter, Vincent Vieregge, Marie-Christin Weber, Runxin Xu, Hao Chen, Kamacay Cira, Atsuko Kasajima, Helmut Friess, Philipp-Alexander Neumann, Nazila Kamaly
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Anastomosis
Intestinal surgery
Inflammatory bowel diseases (IBD)
Inflammation
Resolution of inflammation
Annexin A1
Online Access:https://doi.org/10.1038/s41598-024-80886-1
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https://doi.org/10.1038/s41598-024-80886-1

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