Optimal strategy of new 6H-1,3,4-thiadiazines synthesis in search of the promising antidiabetic agents

Optimal strategy of new 6H-1,3,4-thiadiazines synthesis in search of the promising antidiabetic agents

In this work, we report a convenient method for the preparation of new 2-hydroxyethylamino-substituted 6Н-1,3,4-thiadiazine hydrobromides for the search of new agents with pleiotropic (antioxidant and antiglycating) activity. The synthesis is based on the cyclocondensation reaction of 4-substituted...

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Bibliographic Details
Main Authors: Tatiana A. Tseitler, Larisa P. Sidorova, Alla V. Ivanova, Oleg N. Chupakhin
Format: Article
Language:English
Published: Uralʹskij federalʹnyj universitet imeni pervogo Prezidenta Rossii B.N. Elʹcina 2024-11-01
Series:Chimica Techno Acta
Subjects:
1,3,4-thiadiazine
antioxidant activity
cyclocondensation reaction
4-substituted thiosemicarbazide
antidiabetic agent
Online Access:https://chimicatechnoacta.ru/article/view/8108
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