Multiparametric grading of glaucoma severity by histopathology can enable post-mortem substratification of disease state
Abstract Neurodegeneration in glaucoma patients is clinically identified through longitudinal assessment of structure–function changes, including intraocular pressure, cup-to-disc ratios from fundus images, and optical coherence tomography imaging of the retinal nerve fiber layer. Use of human post-...
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Main Authors: | Chuanxi Xiang, VijayKrishna Raghunathan, Yubin Qiu, Manisha Mehta, John T. Demirs, Cynthia L. Grosskreutz, Christopher W. Wilson, Ganesh Prasanna |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40478-024-01880-2 |
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