Formalin and 2.5% Glutaraldehyde/2% Paraformaldehyde in 0.1 M Cacodylate Buffer Inactivation Protocols to Ensure the Proper Fixation of Positive Sense RNA Viruses and Genomic Material Prior to Removal from Containment

Recommendations released by the CDC in 2023 address the need to demonstrate that the RNA genome of positive-strand RNA viruses is inactivated in addition to viral particles. This recommendation is in response to the similarities between host mRNA and the viral genome that allow the viral RNA to be u...

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Bibliographic Details
Main Authors: Lauren E. Panny, Ashley E. Piper, Christina L. Gardner, Crystal W. Burke
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Methods and Protocols
Subjects:
Online Access:https://www.mdpi.com/2409-9279/7/6/105
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