Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesis

Abstract PDGFRA+ cells have been identified as adipocyte stem cells (ASCs) that differentiate into beige adipocytes in white adipose tissue (WAT) following thermogenic stimuli. To elucidate the molecular heterogeneity of ASCs, we conducted single-cell transcriptomic profiling of PDGFRA+ cells isolat...

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Bibliographic Details
Main Authors: Dong Soo Kyung, Eunmin Lee, Sehyun Chae, Yeonho Son, Ye-Jin Moon, Daehee Hwang, Jong Kyoung Kim, Yun-Hee Lee, Je Kyung Seong
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01252-9
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