The SOX11:SMARCA4 complex is a driver of oncogenic transcriptional programs in mantle cell lymphoma

The SOX11:SMARCA4 complex is a driver of oncogenic transcriptional programs in mantle cell lymphoma

Abstract Mantle cell lymphoma (MCL) is considered one of the most aggressive B-cell lymphoid neoplasms. The transcription factor SOX11 is aberrantly expressed in conventional aggressive MCL, while it is not or weakly expressed in the leukemic non-nodal MCL subtype with a predominantly indolent clini...

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Main Authors: Anna De Bolòs, Maria Carreras-Caballé, Marta Sureda-Gómez, Marta-Leonor Rodríguez, Stella Charalampopoulou, Robert Albero, Alba Maiques-Diaz, Heribert Playa-Albinyana, Guillem Clot, Cristina López, Dolors Colomer, José I Martin-Subero, Elías Campo, David Reverter, Josep Villanueva, Virginia Amador
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Blood Cancer Journal
Online Access:https://doi.org/10.1038/s41408-025-01333-6
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https://doi.org/10.1038/s41408-025-01333-6

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