Mesenchymal stem cell-derived exosomes carrying miR-486-5p inhibit glycolysis and cell stemness in colorectal cancer by targeting NEK2

Abstract Colorectal cancer (CRC) is a major global concern. Mesenchymal stem cell-derived exosomes (MSC-EXOs) have demonstrated efficacy as a therapeutic approach for colorectal cancer. However, the precise mechanism by which MSC-EXOs treat colorectal cancer remains unclear. Human umbilical cord (hU...

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Bibliographic Details
Main Authors: Facai Cui, Yu Chen, Xiaoyu Wu, Weifeng Zhao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-024-13086-9
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