Transcriptomic characterisation of acute myeloid leukemia cell lines bearing the same t(9;11) driver mutation reveals different molecular signatures

Transcriptomic characterisation of acute myeloid leukemia cell lines bearing the same t(9;11) driver mutation reveals different molecular signatures

Abstract Background Acute myeloid leukemia (AML) is the most common type of acute leukemia, accounting for 20% of cases in children and adolescents. Genome-wide studies have identified genes that are commonly mutated in AML, including many epigenetic regulators involved in either DNA methylation (DN...

Full description

Saved in:
Bibliographic Details
Main Authors: Elise Georges, William Ho, Miren Urrutia Iturritza, Lel Eory, Kamila Malysz, Ulduz Sobhiafshar, Alan L. Archibald, Daniel J. Macqueen, Barbara Shih, David Garrick, Douglas Vernimmen
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Genomics
Subjects:
Leukemia
Acute myeloid leukemia
Comparative transcriptomics
Zinc finger (ZNF) transcriptional repressors
Online Access:https://doi.org/10.1186/s12864-025-11415-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12864-025-11415-1

Similar Items