Efficient Access to New Thienobenzo-1,2,3-Triazolium Salts as Preferred Dual Cholinesterase Inhibitors

Efficient Access to New Thienobenzo-1,2,3-Triazolium Salts as Preferred Dual Cholinesterase Inhibitors

In previous research, 1,2,3-triazolium salts showed significant biological activity as potential inhibitors of cholinesterase enzymes (ChEs), which are crucial for neurotransmission. In this research, pairs of uncharged thienobenzo-triazoles and their charged salts were prepared in order to further...

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Bibliographic Details
Main Authors: Milena Mlakić, Maja Sviben, Ana Ratković, Anamarija Raspudić, Danijela Barić, Ivana Šagud, Zlata Lasić, Ilijana Odak, Irena Škorić
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomolecules
Subjects:
cholinesterase inhibition
docking
genotoxicity
1,2,3-triazolium salts
Online Access:https://www.mdpi.com/2218-273X/14/11/1391
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