Oral delivery of the non-β-blocking R-carvedilol enantiomer for skin cancer chemoprevention in SKH-1 mice

Oral delivery of the non-β-blocking R-carvedilol enantiomer for skin cancer chemoprevention in SKH-1 mice

Abstract Purpose Skin cancer remains the most prevalent cancer worldwide with its incidence continuously rising. Previous studies have demonstrated the efficacy of the β-blocker carvedilol and its non-β-blocking enantiomer R-carvedilol in mitigating UV-induced skin carcinogenesis through topical app...

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Bibliographic Details
Main Authors: Pabitra K. Sardar, Steven Yeung, Ruby Tow, Jacqueline Luga, Matthew Huang, Ayaz Shahid, Bradley T. Andresen, Ying Huang
Format: Article
Language:English
Published: SpringerOpen 2025-01-01
Series:AAPS Open
Subjects:
Carvedilol
R-carvedilol
Chemoprevention
Skin cancer
SKH-1
Online Access:https://doi.org/10.1186/s41120-024-00103-1
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