Molecular mechanisms responsible KPC-135-mediated resistance to ceftazidime-avibactam in ST11-K47 hypervirulent Klebsiella pneumoniae

Molecular mechanisms responsible KPC-135-mediated resistance to ceftazidime-avibactam in ST11-K47 hypervirulent Klebsiella pneumoniae

Ceftazidime-avibactam resistance attributable to the blaKPC-2 gene mutation is increasingly documented in clinical settings. In this study, we characterized the mechanisms leading to the development of ceftazidime-avibactam resistance in ST11-K47 hypervirulent Klebsiella pneumoniae that harboured th...

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Bibliographic Details
Main Authors: Qingyu Shi, Siquan Shen, Chengkang Tang, Li Ding, Yan Guo, Yang Yang, Shi Wu, Renru Han, Dandan Yin, Fupin Hu
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Carbapenem-resistant Klebsiella pneumonia
ST11-K47
hypervirulent
ceftazidime-avibactam
blaKPC-135
blaKPC-2
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2361007
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https://www.tandfonline.com/doi/10.1080/22221751.2024.2361007

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