Challenges and Opportunities in DNA Encoded Library Screens

In our lab we have been developing techniques that attempt to capture or amplify signals in pooled compound mixtures for several years. DNA encoded libraries (DELs) are the most widely used pooled mixtures in early drug discovery. DELs are massive collections of small molecules, where each individua...

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Bibliographic Details
Main Authors: Basilius Sauter, Pinwen Cai, Koder Dagher, Chiara Disraeli, Athira Kakkolliyil Prakash, Lukas Schneider, Ángel Cores Esperon, Dennis Gillingham
Format: Article
Language:deu
Published: Swiss Chemical Society 2025-03-01
Series:CHIMIA
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Online Access:https://www.chimia.ch/chimia/article/view/7887
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