CD40 ligation-induced ERK activation leads to enhanced radiosensitivity in cervical carcinoma cells via promoting autophagy

CD40 ligation-induced ERK activation leads to enhanced radiosensitivity in cervical carcinoma cells via promoting autophagy

CD40, a member of the tumor necrosis factor (TNF) receptor superfamily, plays an important role not only in the immune system but also in tumor progression. CD40 ligation reportedly promotes autophagy in immune cells. However, the effects of CD40 ligation on autophagy and its mechanism in solid tumo...

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Bibliographic Details
Main Authors: Liu Baocai, Zhang Yadong, Wang Quan, Wang Qian, Wang Zhixin, Feng Li
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
CD40
autophagy
radiosensitivity
cervical cancer
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2024229
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