Machine learning algorithms for prediction of cerebrospinal fluid leakage after posterior surgery for thoracic ossification of the ligamentum flavum

Abstract To develop and validate a machine-learning (ML) model that pre-operatively predicts cerebrospinal-fluid leakage (CSFL) after posterior decompression for thoracic ossification of the ligamentum flavum (TOLF), and to elucidate the key risk factors driving model decisions. Electronic medical-r...

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Bibliographic Details
Main Authors: Ruizhou Guo, Ben Liu, Yunqi Wu, Yilu Zhang, Xiyang Wang, Dingyu Jiang, Zheng Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-07430-7
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