In silico and in vivo screening of triamterene synthetic analogues as promising diuretics

The modification of lead-compound aimed to the increasing of activity, decrement of toxicity or improvement of selectivity is one of the most important methods used for elaboration of novel medications. Natural compounds, approved or investigational drugs or just compounds with proved biological act...

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Bibliographic Details
Main Authors: K.V. Sokolova, V.V. Stavytskyi, O.Yu. Voskoboinik, O.A. Podpletnya, S.I. Kovalenko
Format: Article
Language:English
Published: Dnipro State Medical University 2022-09-01
Series:Medičnì Perspektivi
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Online Access:http://journals.uran.ua/index.php/2307-0404/article/view/265739
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