Osthole mitigates the myofibroblast properties in oral submucous fibrosis by suppressing the TGF-β/smad2 signaling pathway and NCK-AS1 expression

Osthole mitigates the myofibroblast properties in oral submucous fibrosis by suppressing the TGF-β/smad2 signaling pathway and NCK-AS1 expression

Background/purpose: Natural products are gaining increasing recognition as an alternative source for alleviating fibrosis as they can regulate various mediators or pathways against fibrosis by targeting non-coding RNAs. In the current study, we aimed to investigate the therapeutic effects of osthole...

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Main Authors:	Po-Yu Yang, Pei-Ling Hsieh, Jung-Chun Yeh, Chun-Te Ho, Yi-Wen Liao, Yu-Lei Wei, Shih-Min Wang, Cheng-Chia Yu, Pei-Ming Chu
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Series:	Journal of Dental Sciences
Subjects:	Oral submucous fibrosis Myofibroblast TGF-β Long non-coding RNA NCK1-AS1
Online Access:	http://www.sciencedirect.com/science/article/pii/S1991790224002836
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