Structural basis for substrate recognition mechanism of human SLC26A7

Structural basis for substrate recognition mechanism of human SLC26A7

Abstract Solute carrier family 26 (SLC26) mainly mediates transmembrane transport of various anion ions, including chloride and other halide ions, bicarbonate, oxalate, and sulfate. Many severe hereditary human diseases are correlated with SLC26 protein mutations. Here we report cryo-EM structures o...

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Main Authors: Xiaorong Li, Xiaoxu Yang, Xiaoli Lu, Bingqian Lin, Yuanyuan Zhang, Bangdong Huang, Yutong Zhou, Jing Huang, Kun Wu, Qiang Zhou, Ximin Chi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-62792-w
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https://doi.org/10.1038/s41467-025-62792-w

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