Apoptotic body based biomimetic hybrid nanovesicles to attenuate cytokine storms for sepsis treatment

Apoptotic body based biomimetic hybrid nanovesicles to attenuate cytokine storms for sepsis treatment

Abstract Sepsis is a severe immune response to pathogens that is associated with high mortality rate and a paucity of efficacious treatment options. It is characterized by the hyperactivation of macrophages and the occurrence of cytokine storms. Given the anti-inflammatory properties of M2 macrophag...

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Bibliographic Details
Main Authors: Hongbing Lan, Zhanhao Zhou, Qian Hu, Qi Xie, Xiaonan Li, Tianyi Tian, Yi Wang, Conglian Yang, Li Kong, Dehao Fu, Yuanyuan Guo, Zhiping Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Sepsis
Macrophages
Cytokine storm
Apoptotic body
Biomimetic carrier
Online Access:https://doi.org/10.1186/s12951-024-03058-3
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https://doi.org/10.1186/s12951-024-03058-3

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