The association between altitude and cerebral small vessel disease burden in the Tibetan population: a cross-sectional study

The association between altitude and cerebral small vessel disease burden in the Tibetan population: a cross-sectional study

Abstract Cerebral small vessel disease (CSVD) is a major neurovascular contributor to stroke and cognitive impairment, yet its interaction with chronic high-altitude adaptation remains poorly understood. This first neuroimaging investigation examined 499 Tibetan natives residing at 2000–4800 m using...

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Bibliographic Details
Main Authors: Shaoli Yao, Zhen-rong Qi, Shi-min Bao, Yi-yin Xing, Hui-ru Feng, Yuling Tan, Qi Zhang, Wei-hong Ge, Xiaorong Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
CSVD burden
Altitude
Tibetan Plateau
Observational study
MRI biomarkers
High-altitude adaptation
Online Access:https://doi.org/10.1038/s41598-025-09891-2
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https://doi.org/10.1038/s41598-025-09891-2

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