USP53 Drives Ethanol-Induced Myocardial Injury by Promoting K63 Deubiquitination-Dependent RIPK1 Activation at K377

USP53 Drives Ethanol-Induced Myocardial Injury by Promoting K63 Deubiquitination-Dependent RIPK1 Activation at K377

Alcoholic cardiomyopathy (ACM) is a type of dilated cardiomyopathy unrelated to ischemia, which develops as a consequence of chronic alcohol consumption. While ethanol-induced irreversible cardiomyocyte death is implicated in ACM development and progression, the precise molecular mechanisms involved...

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Main Authors: Jichen Pan, Xiaolin Liu, Xiao Li, Shanshan Wang, Yuliang Zhao, Chong Yuan, Dongdong Liu, Liyan Wang, Meng Zhang, Fengming Liu, Mei Zhang, Shen Dai
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2025-01-01
Series:Research
Online Access:https://spj.science.org/doi/10.34133/research.0823
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https://spj.science.org/doi/10.34133/research.0823

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