Polymorphisms in the Pfcrt, Pfmdr1, and Pfk13 genes of Plasmodium falciparum isolates from southern Brazzaville, Republic of Congo

Polymorphisms in the Pfcrt, Pfmdr1, and Pfk13 genes of Plasmodium falciparum isolates from southern Brazzaville, Republic of Congo

Abstract This study aimed to analyze polymorphisms in Pfcrt, Pfmdr1, and Pfk13 genes’ markers of resistance to Artemisinin-based combination therapy (ACT), in Plasmodium falciparum isolates from southern Brazzaville, 15 years after the adoption of ACT in the Republic of Congo. A total of 369 microsc...

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Main Authors: Marcel Tapsou Baina, Jean Claude Djontu, Jacques Dollon Mbama Ntabi, Claujens Chastel Mfoutou Mapanguy, Abel Lissom, Christevy Jeannhey Vouvoungui, Reauchelvy Kamal Boumpoutou, Alain Maxime Mouanga, Etienne Nguimbi, Francine Ntoumi
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Plasmodium falciparum
Pfcrt
Pfmdr1
Pfk13
Polymorphism
Republic of Congo
Online Access:https://doi.org/10.1038/s41598-024-78670-2
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https://doi.org/10.1038/s41598-024-78670-2

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