Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population
Objectives. The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing not only in India but also globally. The aim of this observational study was to determine the clinico-pathological findings of NAFLD patients in two different geographic populations in India. Material and methods. T...
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| Language: | English |
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Amaltea Medical Publishing House
2024-09-01
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| Series: | Romanian Medical Journal |
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| Online Access: | https://rmj.com.ro/articles/2024.3/RMJ_2024_3_Art-08.pdf |
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| author | Prangya Paramita Sahoo Mukta Singh Dibyalochan Prahraj Dawesh Prakash Yadav Ayaskanta Singh Kanishka Uthansigh Girish Kumar Pati |
| author_facet | Prangya Paramita Sahoo Mukta Singh Dibyalochan Prahraj Dawesh Prakash Yadav Ayaskanta Singh Kanishka Uthansigh Girish Kumar Pati |
| author_sort | Prangya Paramita Sahoo |
| collection | DOAJ |
| description | Objectives. The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing not only in India but also globally. The aim of this observational study was to determine the clinico-pathological findings of NAFLD patients in two different geographic populations in India. Material and methods. This hospital-based cross-sectional study involved 140 consecutive patients with NAFLD from four centers, primarily diagnosed by ultrasound in Uttar Pradesh (Varanasi) and Odisha (Khordha). Clinical and sociodemographic data were collected from each patient of both the states and were compared. Outcomes. The study findings revealed that most of NAFLD patients were males (71.4%), aged around 39.6±10.86 years, with BMI indicating overweight (27.68 ± 4.25 Kg/m2). Patients from Uttar Pradesh (UP) had non-significantly higher rates of elevated transaminase levels [SGOT/SGPT- 40.2 (41.53)/47.35(60.93) IU/L], compared to those from Odisha [SGOT/SGPT-26(23.15)/29(45.40) IU/L]. Too cases of Odisha had non-significantly higher mean triglyceride levels compared to patients of UP. There was a significant difference in family type in-between the 2 regions (p=0.000), with Odisha having more number of nuclear families compared to UP. Cases from Odisha had non-significantly higher per capita monthly income (41.891 ± 43.23 INR) compared to UP (34.276 ± 27.66 INR). Statistically significant dietary preferences, were noticed in-between the 2 states with majority from Odisha favoring non-vegetarian diets (90.6%) compared to Uttar Pradesh (75.06%). Conclusions. Patients from Odisha had higher per capita monthly income, history of higher non-vegetarian diet consumption, higher hypertriglyceridemia and lesser transaminases compared to cases from Uttar Pradesh. |
| format | Article |
| id | doaj-art-669403ae194f4d91a8c9ca7d7acb3091 |
| institution | Kabale University |
| issn | 1220-5478 2069-606X |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Medical Journal |
| spelling | doaj-art-669403ae194f4d91a8c9ca7d7acb30912025-01-07T12:43:09ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2024-09-0171326026610.37897/RMJ.2024.3.8Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian populationPrangya Paramita Sahoo0Mukta Singh1Dibyalochan Prahraj2Dawesh Prakash Yadav3Ayaskanta Singh4Kanishka Uthansigh5Girish Kumar Pati6Department of Home Science, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi, Uttar Pradesh, IndiaDepartment of Home Science, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi, Uttar Pradesh, IndiaDepartment of Gastroenterology and Hepatology, Kalinga Institute of Medical Sciences, KIITD University Bhubaneswar, Odisha, IndiaDepartment of Gastroenterology, Sir Sunderalal Hospital, Banaras Hindu University, Varanasi, Uttar Pradesh, IndiaDepartment of Gastroenterology, SUM Ultimate Medicare, Bhubaneswar, Odisha, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, SODU Bhubaneswar, Odisha, IndiaDepartment of Gastroenterology, Institute of Medical Sciences and SUM Hospital, SODU Bhubaneswar, Odisha, IndiaObjectives. The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing not only in India but also globally. The aim of this observational study was to determine the clinico-pathological findings of NAFLD patients in two different geographic populations in India. Material and methods. This hospital-based cross-sectional study involved 140 consecutive patients with NAFLD from four centers, primarily diagnosed by ultrasound in Uttar Pradesh (Varanasi) and Odisha (Khordha). Clinical and sociodemographic data were collected from each patient of both the states and were compared. Outcomes. The study findings revealed that most of NAFLD patients were males (71.4%), aged around 39.6±10.86 years, with BMI indicating overweight (27.68 ± 4.25 Kg/m2). Patients from Uttar Pradesh (UP) had non-significantly higher rates of elevated transaminase levels [SGOT/SGPT- 40.2 (41.53)/47.35(60.93) IU/L], compared to those from Odisha [SGOT/SGPT-26(23.15)/29(45.40) IU/L]. Too cases of Odisha had non-significantly higher mean triglyceride levels compared to patients of UP. There was a significant difference in family type in-between the 2 regions (p=0.000), with Odisha having more number of nuclear families compared to UP. Cases from Odisha had non-significantly higher per capita monthly income (41.891 ± 43.23 INR) compared to UP (34.276 ± 27.66 INR). Statistically significant dietary preferences, were noticed in-between the 2 states with majority from Odisha favoring non-vegetarian diets (90.6%) compared to Uttar Pradesh (75.06%). Conclusions. Patients from Odisha had higher per capita monthly income, history of higher non-vegetarian diet consumption, higher hypertriglyceridemia and lesser transaminases compared to cases from Uttar Pradesh.https://rmj.com.ro/articles/2024.3/RMJ_2024_3_Art-08.pdfnafldoverweightdietary choiceslftrisk factorssocio-economic statusregional differences |
| spellingShingle | Prangya Paramita Sahoo Mukta Singh Dibyalochan Prahraj Dawesh Prakash Yadav Ayaskanta Singh Kanishka Uthansigh Girish Kumar Pati Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population Romanian Medical Journal nafld overweight dietary choices lft risk factors socio-economic status regional differences |
| title | Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population |
| title_full | Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population |
| title_fullStr | Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population |
| title_full_unstemmed | Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population |
| title_short | Non-alcoholic fatty liver disease (NAFLD): A comparative study of clinico-socio-demographic characteristics among two diverse Indian population |
| title_sort | non alcoholic fatty liver disease nafld a comparative study of clinico socio demographic characteristics among two diverse indian population |
| topic | nafld overweight dietary choices lft risk factors socio-economic status regional differences |
| url | https://rmj.com.ro/articles/2024.3/RMJ_2024_3_Art-08.pdf |
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